Structure-Dependent Interactions

Three-dimensional structures adopted by DNA and RNA dictate the precise interactions between proteins and nucleic acids which form the basis of gene regulation. Structure-dependent interactions between molecular structures such as G-quadruplexes, triplex DNA, and RNA hairpins perform essential functions in biological processes such as gene replication and transcription while also influencing epigenetic modifications and contributing to disease development like cancer. Creative Diagnostics provides a full range of services that employ near-infrared microarray protein chip technology for advanced high-throughput and high-sensitivity analysis of essential structure-dependent interactions for drug discovery and functional genomics research.